A high-strength steel composite eccentrically braced frame (HSS-EBF) is a new type of seismic structure system. A simplified HSS-EBF analysis model was established using the ABAQUS software to analyze its seismic performance. The overall model of a 10-story HSS-EBF example was developed after the validity of the simplified analysis model was verified. Subsequently, the hysteretic behavior of this example was analyzed by simultaneously applying vertical load and horizontal inverted triangular cyclic load. The results denoted that the simplified HSS-EBF analysis model can accurately simulate the ductility and lateral stiffness as well as dffectively predict the deformation and nonlinear performance of the HSS-EBF structure.