Because of the problems of high time delay, poor security, and transmission congestion in the seismic data transmission system, a Python-based real-time data transmission system is proposed in this paper. The system hardware consists mainly of modules for video transcoding, an interactive interface for Python, a module for data transmission, and a module for system maintenance. The video transcoding can be is possible by Un-encapsulation, decoding, video data storage, coding, encapsulation, etc. Using the Python interactive interface, the interaction between the measurement points and seismic data monitoring center is realized. CDMA transmission mode is combined as a wireless transmission module with VPDN networking mode. The system software is split into two data transmission modes: receiving and sending packets, and the system design is mainly completed by receiving the package. The experimental results show that the system has high response speed, low delay, and superior security, which solves the problem of seismic data congestion.