The large-scale seismicity spatial ordering pattern and the turning characteristics of postseismic activity pattern of moderate-strong earthquake are studied in Qinghai-Xizang block from 1950. The results point out that the appearance of large-scale seismicity spatial ordering before large earthquake is an important stage in the process of strong earthquake development and it can conduct the M_S≥7 earthquake prediction. The breakout or turning of moderate-strong earthquake activity pattern is also an important stage in the process of postseismic activity evolvement, especially the earthquake which breaks down the pattern gives an indication of future seismic activity tendency. There is probability of reoccurring moderate-strong earthquakes or distinct events, and M_S≥7 earthquake in 1~3 year in the region and adjacent areas of earthquake that breaks out the seismic activity pattern.