Research on risk perception of earthquake and its influencing factors helps to reveal the potential risk factors from a public visual angle, and provids basis for decision-making to disaster risk reduction. In this paper Kashgar and Urumqi in Xinjiang are taken as examples and 267 people were investigated by questionnaire. Survey data is analyzed using hypothesis test and Pearson correlation analysis to find out the influencing factors on risk perception such as hazard psychoanalysis, earthquake risk estimation, knowledge level of earthquake and preparedness behaviors for reducing earthquake. The results show that influencing factors include sex, .educational level, income level, family member constitute, building conditions and seismic hazard of resident area. The influencing factors and the risk perception factors link positive or negative feedback chains. Income level as a core factor influences weather the risk perception can be changed to the practical actions of reducing earthquake disaster. Based on the risk analysis, several suggestions for risk reduction are given.