In this work, Holocene-era soft soil deposits in the Pearl River Delta were sampled. The differences in the compression and shear deformation properties of undisturbed and reconstituted soils were determined through uniaxial compression tests, consolidated-undrained triaxial tests, and unconsolidated-undrained triaxial tests. Comparing the compression curves of undisturbed and reconstituted samples revealed that the void ratio of the two soils decreases as pressure increases and is closely related to compression method. The consolidation coefficient of the undisturbed soil sample decreases exponentially as pressure increases, whereas that of the reconstituted soil sample increases linearly with pressure. The results of the triaxial shear test showed that under the same consolidation pressure, the strength of undisturbed samples is lower than that of reconstituted samples. The stress-strain curves of soil samples reflect the occurrence of strain hardening. The influence of confining pressure on the reconstituted soil sample is smaller than that on the undisturbed soil sample.