This paper analyzed the seismogenic characteristics of the Tangshan M5.1 earthquake on July 12, 2020. The nature, seismogenic structure, and rupture mechanism of the earthquake were preliminarily analyzed, then it was speculated that Tangshan fault may be its seismogenic fault. Before the earthquake, the seismicity anomalies in Tangshan area and North China tectonic region were mainly lack of earthquake and significant calm, indicating that the crustal stress in these areas had accumulated to a certain extent. The M5.1 earthquake belongs to the seismic fluctuation activity in the old seismic area of the Tangshan M7.8 earthquake on July 28, 1976. The sequence of the M5.1 earthquake is not rich; the intensity of the earthquake area is low and the feel range is large.