In the preparing process the seismicity in preparing region is undergoing a quick increase process and a quiet process. Thus, the quasi-stable state process of seismisity in the area is upset in the preparing period. The spacial and temporal heterogeneity is clearly shown.
According to the view two indices that indicate the heterogeneity of seismic process in a area were defined: the heteropic degree of seismic frequency F_d and the heteropic degree of seismic energy E_d.
On the basis of expounded theory eight earthquakes (M_s=6) occurred in China have been examined, and the correlation between future earthquake magnitude and abnormal time of F_d and E_d was given. Applying the correlation formula to Diebu earthquake (M_s=5.9, on Jan.8,1987) in Gansu province we achieved good result. The two indices, F_d and E_d, have the meaning for the quantification of earthquake prediction method.