This paper has made a brief introduction to the main achievements and development of the comprehensive earthquake prediction in the Northwestern China.The analyses show that in the aspect of interme-diate-long term tendencies,there is elementary surveying foundation for most destructive earthquakes (M≥5).The results of the comprehensive observation have basically passed statistical tests.There is elementary surveying foundation of short-imminent precursor networks for earthquakes (M≥6.5) only within Urumqi,Lanzhou,Xi'an,Wuzhong and Wudu districts.From 24 seismic cases we get 73 items of intermediate-long term tending anomaly data which are mainly seismometrical ones,53 items of short-imminent anomaly data which are mainly groundwater level,radon,telluric current,This paper has summarized the chief features of temporal and spatial distribution about the anomalies and discussed the new problems and new directions in the comprehensive seismic predictions.