This paper presents a general situation of medium-long term prediction on the 1991 earthquake of Ms7.6 in Burma. The main predicting bases are seismic gap, a Ms6.2 earthquake occurred on March 1,1989 two years before the Ms 7.6 earthquake, and a 300km long seismic zone formed quickly a month after the Ms 6.2 event, and synthetic analysis on situation of M≥7 earthquakes in a large area. The paper also emphatically discusses the relation between the seismic belt and coming great earthquakes.