The Shuiquanjianshan-Juewushan south piedmont fault zone in Jingyuan region, Gansu Province was a strike reverse fault before early Quaternary and became sinistral strike-slip fault in middle Quaternary. As the strong activity occurred along the Haiyuan fault zone, the activities of the Shuiquanjianshan-Juewushan fault zone, other active faults before late Quaternary and com-pressive settling basin within the region were stopped.Obviously, activity of the Quaternary fault was characterized by lateral migration. It is considered that the migration mainly resulted from change of principal stress orientation of regional stress field and characteristic structure boundary condition.