Seismicity feature of different scaled rectangles of Central-America and Beijing region is analyzed to study the hierarchical characteristic of spatial distribution of earthquakes. The result shows that the spatial distribution is hierarchical and scale-invariant. When the studied area is roughly divided into four small regions, the ratio between the number of earthquakes of the small region of which seismicity is high and the number of small region of which seismicity is low is 4 ～ 5. The earthquake distribution of smaller regions divided further possesses the same regularity. And this hierarchy is independent on time and magnitude. The hierarchy of crustal structure is the possible reason for the hierarchy of the earthquake spatial distribution.