The relation between discharge changes of Ligou well, Qingshui and Shiqiao well, Lixian and mid-strong earthquakes in neighboring region is analyzed.It is found that discharges of the two wells rise or undulate about half of year before part of the mid-strong earthquakes in the neighboring region, with a maximum anomalous amplitude of 3.75mL/s.There are no the anomalies of the discharges before the events with smaller magnitude relatively distant from the wells.The reflecting range of the anomalies of the two wells to M_S5 events is 250 km, that to M_S6 events is 350 km and that to M_S7 events is 500km.