Activity characteristics of strong earthquakes in Keping block, Xinjiang since 1969 are analy zed.It is found that the strong earthquakes in the block periodically and circularity occur and the periods are corresponding with active periods of strong earthquakes of Xinjiang region.The seismicities of Xikeer and Wushi small region in the Keping block have a certain significance to prediction of M_S ≥ 6 earthquakes in the block.After a M_S ≥ 6 earthquakes, activities of M_S ≥ 4.5 earthquakes in the block indicated places of coming strong earthquakes in a certain extent.