The correlation of earthquakes with M_S ≥ 7.0 in interior Tibet plateau and Burma transform tectonic region, southwestern of Yongnan region is studied.The results show that the spatio-temporal co rrelation is among earthquake very obvious in Tibet plateau and its adjacent regions. The main features of seismicity are cluster in temporal, migration in space and order in migratory route. In each cluster, usually the events first occurred in Burma transform tectonic region and southwestern of Yongnan, then migrate to the Southnorthern Seismic Belt and interior Tibet along two routes, with complete pattern.