When the bridge piers with shallow foundation subject to strong earthquake action, the uplift of foundations will occur and the foundation soil will enter to plasticity, meanwhile the structure will enter to nonlinear state and is damaged. It is very difficult to simulate the uplift and yield of supporting soil using an accurate method. In this paper,an improved Winkler foundation model, which could be used to consider uplift and yield, is employed in the seismic response analysis. Taking the project of Xiaoxihu Yellow River Bridge in Lanzhou city as the example,an artificial seismic wave with the site transcendental probabity 10% level is inputted and the nonlinear history responses are obtained. The result shows that the displacement on top of the pier increases and the moment at bottom of the pier decreases, the piers will yield whert meat strong earthquake, but its curvature will not bead constructure. So the goal of three-level aseismic design can be meat.