This study surveyed and analyzed the significant mutations of the original observations including observing systems of movement，the natural environment，and buildings affected facilities by examining resistivity observations at Changli station from January 1999 to May 2013. On the basis of this analysis，Changli station has used the curve tracking application and normalized variation rate method （NVRM）approach to analyze earthquakes occurring in the Chinese mainland and the surrounding region since 2000，which include the November 14，2001，West Kunlun Mountain Pass MS8.1 earthquake；the December 26，2004，Sumatra MS8.9 earthquake；the May 12，2008，Wenchuan MS8.0 earthquake；the March 11，2011，level 4 far MS9.0 earthquake in Japan；and the resistivity change of 400 km near Changli station before the earthquakes occurred. The results show a relationship among two trends and three record-breaking abnormalities and far earthquakes in addition to a relationship between these earthquakes and changes in the mechanical state of North crust in a wide range of backgrounds. According to the analysis of nine moderate earthquakes in Bohai area，five occurred within six months of abnormalities，including the abnormal frequency of EW Road between 2008 and 2009 and between 2012 and 2013 and that of NS Road in 2009.Based on the differences in intensity，seismic studies at various distances consider that the analysis of abnormal signals should be combined with the record-breaking abnormal changes，trend changes and transitions，and NVRM processing and analysis methods to analyze observations of Earth resistivity.These differences may be related to the strong earthquakes if there is a distortion or trend in abnormalities lasting 6 to 24 months. However，the level 4 and 5 earthquakes do not generally cause distortions or trend changes.