The seismic resistance of structures involves uncertainty regarding the structure and the earthquake,and is coupled with non-linear variables.This paper employs Incremental Dynamic Analysis (IDA) to analyze the earthquake uncertainties.Based on OpenSEES finite element modeling theory,16 ground motion records were selected.After a discussion on the seismic vulnerability of 13 plane frame structures,this paper clarifies the influence of 4 parameters on the seismic resistance levels that RC frame structures can attain.These parameters are axial compression ratio,height-width ratio,concrete strength,and longitudinal reinforcement strength.The results show that RC frame constructions,which are designed in strict accordance with current specifications,can meet the target of "no collapse in a large earthquake"; the influence of the height-width ratio on seismic resistance is not obvious; on the premise of similar axial compression ratios,increase in concrete strength can improve the seismic resistance of structures.Under the same earthquake,for structures with high beam-column longitudinal reinforcement strength,the probability of reaching the immediate occupancy and life safe states is larger than that of structures with low beam-column longitudinal reinforcement strength,but the latter show better collapse resistance.