In this paper, we design and complete a shaking table model test with respect to slope with a scale of 1:100, and discuss the similarity relation of the model, sensor layout, and process of model construction, as well as the seismic wave loading system. We built the model slope in soil with a height of 50 cm, length of 100 cm, and thickness of 45 cm, and performed a series of tests with inputs of different seismic wave types, amplitudes, and frequencies. We discuss the dynamic characteristics and responses of the slope in an earthquake and the influence of the ground motion parameters. The results show that the acceleration responses at the same slope position have obvious differences under different seismic loading inputs. The amplification coefficients of acceleration along the slope surface and in the vertical direction increase smoothly with increasing elevation, and otherwise increases dramatically in the slope body. At the same time, the input frequency of seismic waves has obvious effects on the dynamic slope responses. As it approaches the natural frequency of the model slope, the amplification effect of acceleration is clearly enhanced with increasing frequency. The amplification coefficients of acceleration on the slope surface are larger than those in the slope body at the same elevation. The amplification coefficients of acceleration decrease with increasing earthquake amplitudes. With an increase in vibration number, the damping ratios increase, and the amplification coefficients of peak acceleration in the slope decrease with increases in the seismic amplitudes. Based on the shaking table test results, we present the influence of the ground motion parameters on the dynamic slope characteristics. The acceleration amplification coefficients increase nonlinearly as the elevation increases, and the distribution of acceleration in slope changes as the input seismic wave frequency changes. Acceleration amplification coefficients increase with increments of seismic wave amplitude, but amplitude does not change the distribution of acceleration in the slope body. The duration time of the input seismic wave has little influence on the distribution and amplitude of acceleration in the slope. These results help reveal the mechanism of slope instability during earthquakes, and can provide valuable references for aseismic slope engineering design.