Based on 2001-2015 flow and continuous GPS observation data, the horizontal velocity field model of Weihe basin is established in this study using the Hardy function interpolation method, and the strain characteristic parameters in spherical coordinates were calculated. Based on the geological tectonic background of the Shaanxi area, the distribution characteristics of horizontal velocity field and strain field in the Weihe basin are analyzed. The results show the following:(1) The GPS velocity field in the Western Weihe basin was obviously affected by the combined action of Qinghai-Tibet block and Erdos block, and the GPS velocity field in the western region is larger than that in central and eastern regions, which the GPS velocity field rotates clockwise. (2) The change of main stress field in the Western Weihe basin is complicated, while the change of the main strain in the Xi'an area is obvious, corresponding to the Gaoling M_S4.4 earthquake on November 05, 2009. (3) The changes of principal strain, maximum shear strain, and plain strain during 2001-2010 are more obvious than those during 2011-2015, indicating the stress field in the whole Weihe basin has been released and adjusted after the Gaoling M_S4.4 earthquake, and the earthquake urgency has been relatively low in the Weihe basin.