Evaluating the damage resistance of reinforced concrete structures has great engineering significance, but the current evaluation method based on single-factor superposition has a large error factor. To solve this problem, in this paper, we propose a method for evaluating the seismic vulnerability of reinforced concrete structures based on multiple fuzzy analysis. Based on the Park-Ang seismic damage model, we introduce normalized cumulative energy dissipation parameters to obtain the inter-story damage of the building structure, and we obtain the integral damage values of a post-earthquake building structure via a weighted average. Then, we use the story-drift-ratio parameters to calculate the story drift ratio of the post-earthquake structure. We take the integral damage values of post-earthquake structures and the story drift ratio as the multi-factor domain to perform a multiple fuzzy evaluation of the structural damage resistance. We select the mathematical model and membership function of the fuzzy damage assessment to calculate the weight of each factor and the comprehensive damage index of the structure. The experimental results show that the accuracy of the proposed method based on multiple fuzzy analysis is greater than 95%, which confirms its effectiveness for evaluating the damage resistance of reinforced concrete structures.