The development of earthquake prevention and disaster mitigation needs the support of high technology, so it is important to accurately grasp the global development trend of earthquake prevention and disaster mitigation from the perspective of patent. Based on global patent database incoPat, this paper revealed the global research status, research hotspots, and R & D layout of technologies in the field of earthquake prevention and disaster reduction. The results showed that the research and development of technologies in the field of earthquake prevention and disaster mitigation has rapidly increased since 2004. The total number and growth rate of patents in China far exceed those in other countries, but the overall quality of patents in the United States is the highest. High value patents mainly include vibration sensors and accelerometers, earthquake early warning systems and alarms, seismic walls and seismic structures, isolation bearings, elevator control devices, earthquake emergency command systems, earthquake emergency disposal and escape devices, disaster relief robots, etc.