On January 8, 2022, an MS6.9 earthquake occurred in Menyuan County, Qinghai Province. It is another strong earthquake occurred in this region after the 2016 Menyuan MS6.4 earthquake, and determining the rupture distribution of this earthquake has great significance for analyzing the seismic damage risk in this area. Based on the observation data from 12 continuous global navigation satellite system (GNSS) stations and 17 mobile stations in the epicenter and its surrounding areas, the GNSS static co- seismic deformation field of 29 stations within 100 km of the epicenter was obtained and the co- seismic slip distribution of the MS6.9 earthquake was inverted. Results show that the maximum deformation observed by near- field GNSS reaches 1.3 m. The optimal rupture model shows that the main rupture zone of the earthquake is concentrated at the depth of 0-10 km; the sliding rupture is exposed to the surface, and the maximum slip is up to 4.07 m; the inverted seismic moment is about 1.1×10¹⁹ N·m, corresponding to MW6.7. The earthquake rupture to the surface is the direct cause of the destruction of infrastructure in this region.