To verify the effectiveness of strengthening the earthen site slope under earthquake, we considered the existing reinforced section of the earthen site slope in the high loess slope of Kashgar, Xinjiang, as the research object. A three-dimensional dynamic analysis model was established using the finite\|element software Midas/GTX NX,and analysis was performed on the deformation control of the earthen site slope reinforced by lattice anchor retaining wall under earthquake. Results indicate the severe displacement and deformation at the top and foot of the slope,the cumulative effect of the increase in earthquake duration. The displacement and deformation in the horizontal and vertical directions were effectively controlled after reinforcement,and the maximum deformation value met the requirements of control. The stability coefficient of the earthen site slope under earthquake reached 1.54 after reinforcement,which meets the requirement value of 1.15 in the code. The research demonstrates that the lattice anchor retaining wall can effectively control the displacement and deformation of the earthen site slope,thus improving slope stability.