On January 2, 2025, two earthquakes of magnitude 4.8 and 4.6 occurred successively in Yongning County and Jinfeng District, located in the central part of the Yinchuan Fault Basin in Ningxia, causing significant social and economic impacts. To quickly obtain the seismic damage from these two earthquakes and further carry out subsequent seismic fortification work in the region, this paper realizes the simulation and analysis of seismic damage to building clusters in key earthquake-affected areas using the nonlinear elastoplastic time-history analysis method, based on the construction of refined ground motion models, geological models, and three-dimensional building models.The results show that building damage is relatively concentrated in the area within 5km of the epicenter, mainly manifested as minor damage caused by insufficient seismic resistance capacity of old buildings and self-built houses. The maximum intensity at the epicenter is VI degree, with no moderate or more severe damage observed. The seismic damage simulation results further reveal the amplification effect of the basin"s sedimentary layers on ground motion and their impact on people"s psychology.The results of this paper can provide important references for improving the seismic resilience and disaster response capabilities of cities with a large stock of old buildings, as well as for emergency response and risk prevention and control of urban direct earthquakes.