To comprehensively assess the baseline seismic disaster risk in the Chongqing section of the Huayingshan fault zone, a methodology combining quantitative evaluation and qualitative indicator system assessment was applied to seven districts traversed by the fault zone. Building inventory and population distribution data were used to estimate economic losses and casualties under seismic events of varying exceedance probabilities. Subsequently, according to regional characteristics, the analytic hierarchy process determined the weight coefficients of single-factor indicators influencing seismic disaster consequences. Disaster reduction capacity indicators were integrated across different administrative districts to delineate seismic risk zones. Rongchang District exhibited the highest seismic vulnerability, followed by Hechuan, Yongchuan, Tongliang, Beibei, Bishan, and Dazu Districts. Hechuan District presented the highest seismic risk level, followed by Bishan, Beibei, Yongchuan, Rongchang, Tongliang, and Dazu Districts. These findings provide critical data to guide local governments in earthquake prevention and disaster reduction, enhancing engineering seismic measures, and optimizing emergency preparedness.