The feature of earthquake ground motion parameters of loess plateau in the eastern Gansu province are analyzed on the basis of geological tectonic environment,historic earthquake influence,building damaging features and earthquake risk probability calculation.The amplification factor and landform zoning of the seismic parameters are studied by the seismic response analysis of loess site and topography characters.The research shows that the earthquake impact is mainly caused by strong earthquake from long distance and the earthquake duration time of ground motion is longer in which the long-period component is abundant.The thick loess and landform have significant amplification to the earthquake ground motion and the seismic parameters have landform zoning behavior.Comparison with the seismic ground motion parameter zonation map,some suggestions to the seismic fortification parameters are proposed for the loess plateau in eastern Gansu province.