In this paper, the actual exploitation situation of deep confined water in Changyi district, Shandong Province is studied, and the relationship between the deep groundwater exploitation and land subsidence in the study area is analyzed in detail. It is found that the control water level of deep confined water is not only the data for controlling water level, but also the reasonable range of water level fluctuation. With the developments in science and technology and the improvement of management level, the fluctuation range of water level can be adjusted timely. In formulating the control water level in plain areas, it should be detailed to each county or township, and the overall control and adjustment should be timely performed.