On September 12, 2018, a M5.3 earthquake occurred at Ningqiang County, Shaanxi Province. Thirty-nine strong motion stations located in this region were fully triggered by the main shock. A total of 117 records of three-component acceleration were obtained by NSMONS. In this paper, we first calculated the ground motion parameters of near-field stations and drew the contour map of peak accelerations near the epicenter. It is then found that the attenuation prediction model of Huo Jun-rong can better reflect the influence field of the earthquake by comparing the observed data with some commonly used ground motion prediction equations. Finally, we compared the acceleration response spectrum of 51GYD station with the design spectrum to summarize the basic characteristics of response spectra for this earthquake. The H/V spectral ratio method was applied to analyze the seismic response of the local site at 51GYD station and 62ZM array. Furthermore, the amplification effect of overburden soil on ground motion and the influence process of local topography on peak acceleration and peak velocity were studied.